Why Tapered Fibers?
Delivering light in a controlled fashion is required to fully exploit the potential of optogenetic techniques in controlling and monitoring neural circuits. A simple and cost-effective device based on a thin Tapered Optical Fiber (TF) that can perform both homogeneous light delivery and dynamically-controlled spatially-restricted illumination.
- Wide-volume illumination can be obtained in both freely-moving and head restrained mice.
- TFs also allow for site selective light delivery.
- Compatibility with both laser and LED light sources.
- In comparison with flat-cleaved optical fibers, TFs are less invasive and capable of achieving a larger illuminated volume and higher penetration depth.
- Possibility of tailoring TF emission lengths up to 3mm through NA value – perfect for deep brain regions.
- Complement existing methods for light delivery in optogenetics experiments and has the potential to replace commonly used flat-faced fibers for many applications.
MCI Currently has two fibers available from OptogeniX:
The Lambda-B Fibers, perfect for illuminating large volumes of tissue.
The Sigma-2 Fibers, ideal for off-axis light delivery.