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Biosensor Adenosine

sarissaprobe® Adenosine / ADO

Measures Adenosine in real time

  • Sensor lengths: 2 mm or 0.5 mm
  • Sensor diameters (μm):  7*, 25 or 50
  • Limit of detection: 50 nM
  • Linear range: 0.2 μM to 20 μM
  • Shelf life (dry storage): 6 weeks

* 7 μm sensors on carbon fibre electrode

Quote request for ADO sensors:  please quote the product code (length-diameter) below:

  • SBS-ADO-05-07
  • SBS-ADO-05-25
  • SBS-ADO-05-50
  • SBS-ADO-20-50

Instructions for use – ADO/INO

Recent papers using sarissaprobe® ADO:

  • Diogenes MJ, Raquel NT, Fucile S, Martinello, K, Scianni M, Theofilas, P Lopatar J,  Ribiero JA, Maggi L, Frenguelli BG, Limatola C, Boison D, Sebastiao AM (2012) Homeostatic Control of Synaptic Activity by Endogenous Adenosine is Mediated by Adenosine Kinase. Cerebral Cortex doi:10.1093/cercor/bhs284.
  • Heinrich A, Ando R, Turi G, Rozsa B, Sperlagh B (2012) K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharm 167:1003-1020.
  • Schmitt LI, Sims RE, Dale N, Haydon PG (2012) Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine. J Neurosci 32:4417-4425.
  • Klyuch BP, Dale N, Wall MJ (2012) Deletion of ecto-5′-nucleotidase (CD73) reveals direct action potential-dependent adenosine release. J Neurosci 32:3842-3847.
  • zur Nedden S et al (2011) Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors. J Neurosci 31:6221-6234.
  • Klyuch B et al (2011) The dynamics of single spike-evoked adenosine release in the cerebellum. J Physiol 589:283-295.
  • User Manual